PXD044536
PXD044536 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative proteome analysis of liver in acute cardiac rejection in mice |
| Description | In order to study the changes of liver protein level in mice with acute cardiac rejection, we established a mouse model of ectopic heart transplantation. According to the matching relationship between recipient and donor, they were divided into the following two groups: allograft group (ALLO), BALB/ C hearts were transplanted into C57BL/6J recipients with complete mismatch of major histocompatibility complex; In the syngeneic transplantation group (ISO), C57BL/6J hearts were transplanted into MHC-matched C57BL/6J recipients. On day 6 after mouse heart transplantation, livers were obtained from recipient mice in the allograft group (n = 3) and from recipient mice in the syngeneic (ISO) group (n = 3). A series of techniques such as protein extraction, enzyme digestion, TMT labeling, HPLC classification, liquid chromatography-mass spectrometry tandem analysis, database search and bioinformation analysis were used to study the quantitative proteome of samples. |
| HostingRepository | iProX |
| AnnounceDate | 2022-09-05 |
| AnnouncementXML | Submission_2023-08-13_19:54:47.932.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Heng Xu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-13 19:54:40 | ID requested | |
| ⏵ 1 | 2023-08-13 19:54:48 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: liver, proteome, TMT, cardiac rejection |
Contact List
| Jizhang Yu | |
|---|---|
| contact affiliation | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| contact email | 986157425@qq.com |
| lab head | |
| Heng Xu | |
| contact affiliation | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
| contact email | 451970487@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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