PXD044474
PXD044474 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Metabolomics insights for acquired platinum chemoresistance of A549 cells induced by chronic arsenic exposure |
| Description | Arsenic exposure is considered as a risk factor for lung cancer. However, toxic effects of the metabolic mechanism responsible for arsenic-induced toxicity and especially chronic effects, are less known. Here we constructed a cell model of lung adenocarcinoma A549 cells by chronic arsenic exposure. Cell-based experiments showed that A549 cells display platinum resistance with chronic exposure of arsenic. The metabolic response of A549 cells to arsenic exposure was profiled by gas chromatography-mass spectrometry. |
| HostingRepository | iProX |
| AnnounceDate | 2023-08-09 |
| AnnouncementXML | Submission_2024-07-31_19:43:18.243.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yang Zhou |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | quadrupole |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-09 20:40:31 | ID requested | |
| ⏵ 1 | 2024-07-31 19:43:18 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Arsenic, A549 cells, metabolomics, chemotherapeutic resistance, GC-MS |
Contact List
| Yang Zhou | |
|---|---|
| contact affiliation | The Affiliated Li Huili Hospital, Ningbo University |
| contact email | zhouyang610@163.com |
| lab head | |
| Yang Zhou | |
| contact affiliation | The Affiliated Li Huili Hospital, Ningbo University |
| contact email | zhouyang610@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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