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PXD044474

PXD044474 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMetabolomics insights for acquired platinum chemoresistance of A549 cells induced by chronic arsenic exposure
DescriptionArsenic exposure is considered as a risk factor for lung cancer. However, toxic effects of the metabolic mechanism responsible for arsenic-induced toxicity and especially chronic effects, are less known. Here we constructed a cell model of lung adenocarcinoma A549 cells by chronic arsenic exposure. Cell-based experiments showed that A549 cells display platinum resistance with chronic exposure of arsenic. The metabolic response of A549 cells to arsenic exposure was profiled by gas chromatography-mass spectrometry.
HostingRepositoryiProX
AnnounceDate2023-08-09
AnnouncementXMLSubmission_2024-07-31_19:43:18.243.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYang Zhou
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
Instrumentquadrupole
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-09 20:40:31ID requested
12024-07-31 19:43:18announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Arsenic, A549 cells, metabolomics, chemotherapeutic resistance, GC-MS
Contact List
Yang Zhou
contact affiliationThe Affiliated Li Huili Hospital, Ningbo University
contact emailzhouyang610@163.com
lab head
Yang Zhou
contact affiliationThe Affiliated Li Huili Hospital, Ningbo University
contact emailzhouyang610@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI