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PXD044418

PXD044418 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleObtaining Increased Functional Proteomics Insights from Thermal Proteome Profiling Experiments through Optimized Melt Shift Calculation and Statistical Analysis
DescriptionHEK293A cells treated with either DMSO or 1 micromolar Thapsigargin for 1 hour. Lysates were heat treated at 8 temperatures and supernatant was reduced, alkylated and digested with Trp/LysC. Samples were desalted and labeled with TMTPro.
HostingRepositoryMassIVE
AnnounceDate2023-08-07
AnnouncementXMLSubmission_2023-08-07_11:11:12.927.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterNeil McCracken
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListL-methionine sulfoxide; Acetyl; Met-loss; Met-loss+Acetyl; TMTpro; Carbamidomethyl
InstrumentOrbitrap Exploris 480; Orbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-07 11:06:58ID requested
12023-08-07 11:11:13announced
Publication List
no publication
Keyword List
submitter keyword: UPR, TPP, Thapsigargin, Unfolded Protein Response
Contact List
Amber L. Mosley
contact affiliationIndiana University School of Medicine
contact emailalmosley@iu.edu
lab head
Neil McCracken
contact affiliationIndiana University
contact emailnamccrac@iu.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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