PXD044328

PXD044328 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Structural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module
Description	The Mediator complex consists of a Core and a dissociable Kinase module. This project is to understand the binding mode between the Core and Kinase module. Both Mediator complex and its Kinase module were individually crosslinked and analyzed by XL-MS.
HostingRepository	PRIDE
AnnounceDate	2024-11-21
AnnouncementXML	Submission_2024-11-20_21:00:05.586.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hee Jong Kim
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-03 09:43:27	ID requested
⏵ 1	2024-11-20 21:00:06	announced

Publication List

Chao TC, Chen SF, Kim HJ, Tang HC, Tseng HC, Xu A, Palao L, Khadka S, Li T, Huang MF, Lee DF, Murakami K, Boyer TG, Tsai KL, Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol Cell, 84(20):3932-3949.e10(2024) [pubmed]
10.1016/j.molcel.2024.09.001;

Chao TC, Chen SF, Kim HJ, Tang HC, Tseng HC, Xu A, Palao L, Khadka S, Li T, Huang MF, Lee DF, Murakami K, Boyer TG, Tsai KL, Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol Cell, 84(20):3932-3949.e10(2024) [pubmed]

10.1016/j.molcel.2024.09.001;

Keyword List

submitter keyword: Human, transcription, Mediator, CDK8

submitter keyword: Human, transcription, Mediator, CDK8

Contact List

Kenji Murakami
contact affiliation	University of Pennsylvania, School of Medicine
contact email	kenjim@pennmedicine.upenn.edu
lab head
Hee Jong Kim
contact affiliation	University of Pennsylvania
contact email	heejong@heejong.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/11/PXD044328
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/11/PXD044328

PRIDE project URI

Repository Record List

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