PXD044324

PXD044324 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	TAP-MS of human BRAT1 and WDR73
Description	Using a combination of proteomics, interaction studies and structural characterization we show that WDR73 and BRAT1 are interactors of the heterodimer INTS9-11 of INT. Both proteins are involved in the stability and formation of the cleavage module of INT consisting of INTS4-9-11.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:51:56.612.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kevin Sabath
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-03 08:02:40	ID requested
1	2024-07-31 02:22:15	announced
⏵ 2	2024-10-22 06:51:57	announced	2024-10-22: Updated project metadata.

Publication List

10.1016/j.molcel.2024.06.032;
Sabath K, Qiu C, Jonas S, Assembly mechanism of Integrator's RNA cleavage module. Mol Cell, 84(15):2882-2899.e10(2024) [pubmed]

10.1016/j.molcel.2024.06.032;

Sabath K, Qiu C, Jonas S, Assembly mechanism of Integrator's RNA cleavage module. Mol Cell, 84(15):2882-2899.e10(2024) [pubmed]

Keyword List

submitter keyword: LC-MS/MS

submitter keyword: LC-MS/MS

Contact List

Dr. Stefanie Jonas
contact affiliation	Institute of Molecular Biology and Biophysics, ETH Zurich,Otto-Stern-Weg 5, CH-8093, Zurich, Switzerland
contact email	Stefanie.Jonas@mol.biol.ethz.ch
lab head
Kevin Sabath
contact affiliation	ETH Zurich
contact email	Kevin.sabath@mol.biol.ethz.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD044324
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD044324

PRIDE project URI

Repository Record List

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