PXD044298

PXD044298 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Elucindating the role of the transcription factor IRF4 in Th17 and Treg cells
Description	- transcription factor interferon regulatory factor 4 (IRF4) = crucial transcription factor for different immune cells, incl pro-inflammatory Th17 and anti-inflammatory Treg cells - IRF4 is essential for the cell differentiation and fate determination - however molecular mechanisms of IRF4-mediated gene expression in fully differentiated Th17/Treg cells are still not fully understood - integration of data derived from affinity-purification and full mass spectrometry-based proteome analysis with chromatin immune precipitation sequencing (ChIP-Seq) - characterization of proteins generally involved in the T cell development as well as subtype-specific differentiation and identification of novel, yet uncharted IRF4 interactors
HostingRepository	jPOST
AnnounceDate	2024-08-02
AnnouncementXML	Submission_2024-08-01_08:00:23.301.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Anna Gabele
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide
Instrument	Orbitrap Exploris 480; timsTOF Pro 2

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-02 05:18:46	ID requested
⏵ 1	2024-08-01 08:00:23	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: mouse, Th17 cells, Treg cells, PPI, knockout, LC-MS, DIA-NN

submitter keyword: mouse, Th17 cells, Treg cells, PPI, knockout, LC-MS, DIA-NN

Contact List

Ute Distler, Tobias Bopp
lab head
Anna Gabele
contact affiliation	Institute for Immunology, University Medical Center Mainz
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002260/