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PXD044248

PXD044248 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInteracting proteins of AMPK studied using TurboID proximity labeling technology
DescriptionBecause AMPK is involved in a variety of metabolic pathways, coupled with the advantages of high catalytic activity and fast labeling of TurboID neighboring labeling technology, a large number of proteins interacting with AMPK gene were found through biotin labeling experiments, and subsequent experiments verified that AMPK and DNAJA1 have interaction, and the two can synergistically protect cells from apoptosis; this has laid a certain theoretical foundation for how to use AMPK to treat clinical diseases such as diabetes and myocardial infarction in the future.
HostingRepositoryiProX
AnnounceDate2023-08-01
AnnouncementXMLSubmission_2023-07-31_22:14:42.364.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterWu Liu
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-07-31 22:14:22ID requested
12023-07-31 22:14:42announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: TurboID, AMPK, DNAJA1, biotin labeling, U251 cells
Contact List
Qingjie Chen
contact affiliationHubei University of Science and Technology
contact emailchenqingjie8858@163.com
lab head
Wu Liu
contact affiliationHubei University of Science and Technology
contact emaillw463684057@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI