PXD044248
PXD044248 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Interacting proteins of AMPK studied using TurboID proximity labeling technology |
Description | Because AMPK is involved in a variety of metabolic pathways, coupled with the advantages of high catalytic activity and fast labeling of TurboID neighboring labeling technology, a large number of proteins interacting with AMPK gene were found through biotin labeling experiments, and subsequent experiments verified that AMPK and DNAJA1 have interaction, and the two can synergistically protect cells from apoptosis; this has laid a certain theoretical foundation for how to use AMPK to treat clinical diseases such as diabetes and myocardial infarction in the future. |
HostingRepository | iProX |
AnnounceDate | 2023-08-01 |
AnnouncementXML | Submission_2023-07-31_22:14:42.364.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Wu Liu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-07-31 22:14:22 | ID requested | |
⏵ 1 | 2023-07-31 22:14:42 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: TurboID, AMPK, DNAJA1, biotin labeling, U251 cells |
Contact List
Qingjie Chen | |
---|---|
contact affiliation | Hubei University of Science and Technology |
contact email | chenqingjie8858@163.com |
lab head | |
Wu Liu | |
contact affiliation | Hubei University of Science and Technology |
contact email | lw463684057@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |