PXD044245

PXD044245 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	PVRL2 suppresses anti-tumor immunity through PVRIG- and TIGIT-independent pathways
Description	Here, we share discovery proteomics data associated with a larger study to expose new immunoregulatory mechanisms in cancer. PVRL2 was identified in both tumor cells and exosomes, and the role of this surface protein in the immune response to cancer was explored in further studies.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:40:32.581.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	James Byrnes
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	2-pyrrolidone-5-carboxylic acid (Glu); acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-31 21:03:45	ID requested
1	2024-05-21 12:04:26	announced
⏵ 2	2024-10-22 06:40:38	announced	2024-10-22: Updated project metadata.

Publication List

Yang J, Wang L, Byrnes JR, Kirkemo LL, Driks H, Belair CD, Aguilar OA, Lanier LL, Wells JA, Fong L, Blelloch R, PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways. Cancer Immunol Res, 12(5):575-591(2024) [pubmed]
10.1158/2326-6066.cir-23-0722;

Yang J, Wang L, Byrnes JR, Kirkemo LL, Driks H, Belair CD, Aguilar OA, Lanier LL, Wells JA, Fong L, Blelloch R, PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways. Cancer Immunol Res, 12(5):575-591(2024) [pubmed]

10.1158/2326-6066.cir-23-0722;

Keyword List

submitter keyword: immunology,cancer

submitter keyword: immunology,cancer

Contact List

James Wells
contact affiliation	Pharmaceutical Chemistry and Molecular and Cellular Pharmacology Departments, University if California, San Francisco
contact email	jim.wells@ucsf.edu
lab head
James Byrnes
contact affiliation	Unviersity of California, San Francisco
contact email	byrnes.jamesr@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD044245
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD044245

PRIDE project URI

Repository Record List

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