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PXD044177

PXD044177 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSecretome analysis of Pancreatic Cancer Spheroid with myeloid cell infiltration
DescriptionPancreatic ductal adenocarcinoma (PDAC) is one of the most hypoxic, lethal, and treatment resistant cancers. Due to its desmoplastic and hypoxic nature along with the abundance of myeloid cell infiltration and scare T cell infiltration, PDAC is considered a cold tumor. Using MiaPaCA-2 as a PDAC spheroid model with hypoxic core grown in serum-free defined media and immune cell infiltration, we assessed the modulation of PDAC secretome and characterized immunomodulatory factors secreted.
HostingRepositoryPRIDE
AnnounceDate2023-12-15
AnnouncementXMLSubmission_2023-12-15_07:04:20.829.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterApple Tay
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; deamidated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-07-28 05:44:10ID requested
12023-12-15 07:04:21announced
Publication List
10.3389/FIMMU.2023.1264012;
Keyword List
ProteomeXchange project tag: Human Proteome Project
submitter keyword: Human, Spheroid, Pancreatic Cancer, PDAC, MiaPaCa2, LC-MS/MS
Contact List
Andreas Lundqvist
contact affiliationKarolinska Institutet, Department of Oncology-Pathology
contact emailandreas.lundqvist@ki.se
lab head
Apple Tay
contact affiliationKarolinska Institute
contact emailapple.tay@ki.se
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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