PXD044177 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Secretome analysis of Pancreatic Cancer Spheroid with myeloid cell infiltration |
Description | Pancreatic ductal adenocarcinoma (PDAC) is one of the most hypoxic, lethal, and treatment resistant cancers. Due to its desmoplastic and hypoxic nature along with the abundance of myeloid cell infiltration and scare T cell infiltration, PDAC is considered a cold tumor. Using MiaPaCA-2 as a PDAC spheroid model with hypoxic core grown in serum-free defined media and immune cell infiltration, we assessed the modulation of PDAC secretome and characterized immunomodulatory factors secreted. |
HostingRepository | PRIDE |
AnnounceDate | 2023-12-15 |
AnnouncementXML | Submission_2023-12-15_07:04:20.829.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Apple Tay |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; deamidated residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-07-28 05:44:10 | ID requested | |
⏵ 1 | 2023-12-15 07:04:21 | announced | |
Publication List
Keyword List
ProteomeXchange project tag: Human Proteome Project |
submitter keyword: Human, Spheroid, Pancreatic Cancer, PDAC, MiaPaCa2, LC-MS/MS |
Contact List
Andreas Lundqvist |
contact affiliation | Karolinska Institutet, Department of Oncology-Pathology |
contact email | andreas.lundqvist@ki.se |
lab head | |
Apple Tay |
contact affiliation | Karolinska Institute |
contact email | apple.tay@ki.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044177
- Label: PRIDE project
- Name: Secretome analysis of Pancreatic Cancer Spheroid with myeloid cell infiltration