PXD044169

PXD044169 is an original dataset announced via ProteomeXchange.

Title	Thermal proteome profiling of sponge whole-body movement
Description	Sponges (Porifera) are early-branching Metazoa who do not possess muscles or neurons, however are able to undergo a whole-body movement that involves the closure of their canal system and collapse of an epithelial tent. In this study we profile proteomic responses of the freshwater sponge Spongilla lacustris during nitric oxide (NO) and agitation induced movements to elucidate the early evolution of coordination. Specifically, we measure condition-dependent changes in protein thermal stability and abundance using Thermal proteome profiling (TPP). These changes are the result of proteins undergoing stabilizing or destabilizing conformational changes broadly caused by e.g. the binding or dissociation of small molecules to the proteins, the formation or loss of protein-protein interactions or a change in post-translational modifications.
HostingRepository	PRIDE
AnnounceDate	2024-01-04
AnnouncementXML	Submission_2024-01-04_08:25:08.714.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Stein
SpeciesList	scientific name: Spongilla lacustris; NCBI TaxID: 6055;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-28 02:52:32	ID requested
⏵ 1	2024-01-04 08:25:09	announced

10.1016/J.CUB.2023.12.021;

submitter keyword: Spongilla,TPP, actomyosin, Evolution

Detlev Arendt
contact affiliation	Developmental Biology Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany Proteomics Core Facility, European Molecular Biology Laboratory, 69117 Heidelberg, Germany
contact email	arendt@embl.de
lab head
Frank Stein
contact affiliation	EMBL
contact email	frank.stein@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD044169

PRIDE project URI

• PRIDE
  1. PXD044169
     1. Label: PRIDE project
     2. Name: Thermal proteome profiling of sponge whole-body movement