PXD044060

PXD044060 is an original dataset announced via ProteomeXchange.

Title	Ribosomal protein signature in adult mouse organs
Description	we purified the ribosomal fraction from 14 different adult mouse tissues and analyzed their protein composition using quantitative mass spectrometry (MS)-based proteomics. We show that ribosomes exhibit heterogeneity in RP composition, not only in the case of RP paralogues (e.g. in muscle and testis, consistent with previous research), but also for several unexpected RPs displaying variability among different organs.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_07:51:17.503.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD044060
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Hesse Anne-Marie
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-25 02:33:00	ID requested
⏵ 1	2025-05-06 07:51:18	announced

10.6019/PXD044060;

Brunchault MR, Hesse AM, Schaeffer J, Fr, ö, hlich A, Saintpierre A, Decourt C, Combes F, Nawabi H, Cout, é Y, Belin S, Proteomics-based characterization of ribosome heterogeneity in adult mouse organs. Cell Mol Life Sci, 82(1):175(2025) [pubmed]

10.1007/s00018-025-05708-7;

submitter keyword: Ribosome,Mouse, quantification, LC-MS/MS

Yohann Couté
contact affiliation	Univ. Grenoble Alpes, INSERM, CEA, UA13 BGE, CNRS, CEA, FR2048, 38000 Grenoble, France
contact email	yohann.coute@cea.fr
lab head
Hesse Anne-Marie
contact affiliation	Laboratoire d'Etude de la Dynamique des Protéomes
contact email	anne-marie.hesse@cea.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD044060

PRIDE project URI

• PRIDE
  1. PXD044060
     1. Label: PRIDE project
     2. Name: Ribosomal protein signature in adult mouse organs