PXD043876

PXD043876 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Top-Down native MS/MS crosslinked alpha synuclein with ion mobility and ECD
Description	Recombinant human alpha synuclein crosslinked with 2.5 molar excess BS2G and BS3 crosslinkers. Buffer exchanged into 50 mM ammonium acetate. MS/MS on singly crosslinked protein by top-down ECD. Final protein concentration 50 uM. Positive mode static nanospray.
HostingRepository	jPOST
AnnounceDate	2023-07-18
AnnouncementXML	Submission_2025-05-15_07:19:20.191.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ian Webb
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	unknown modification; unknown modification; unknown modification
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-18 19:11:45	ID requested
1	2023-07-18 19:14:31	announced
⏵ 2	2025-05-15 07:19:20	announced	2025-05-15: Updated PubMed.

Publication List

Dollar AN, Webb IK, Strategies for Acid and Amine Cross-linking and Labeling for Protein Structural Characterization Using Mass Spectrometry. Anal Chem, 97(15):8213-8219(2025) [pubmed]

Dollar AN, Webb IK, Strategies for Acid and Amine Cross-linking and Labeling for Protein Structural Characterization Using Mass Spectrometry. Anal Chem, 97(15):8213-8219(2025) [pubmed]

Keyword List

submitter keyword: alpha-synuclein, SNCA, ECD, top-down

submitter keyword: alpha-synuclein, SNCA, ECD, top-down

Contact List

Ian Webb
lab head
Ian Webb
contact affiliation	IU Indianapolis
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002253/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002253/