PXD043855

PXD043855 is an original dataset announced via ProteomeXchange.

Title	Disclosing potential therapeutic targets associated with Osimertinib resistance in non-small cell lung cancer cell line H1975
Description	H1975/OSI cell line was induced in vitro through intermittent induction. Cell activity was measured using cell counting kit-8 assay. Uni-omics and multi-omics analyses were conducted on the transcriptomic and proteomic (4D label-free) expression profiles, which involved differential expression analysis, GO functional annotation and KEGG pathway enrichment analysis, correlation analysis of transcription factors, PPI network and Cytoscape analysis.
HostingRepository	iProX
AnnounceDate	2023-07-18
AnnouncementXML	Submission_2024-05-27_21:24:47.703.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xuexia Tong
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-17 19:15:56	ID requested
1	2023-10-30 21:19:12	announced
⏵ 2	2024-05-27 21:24:48	announced	2024-05-28: Update information.

Tong X, Zhang R, Sun R, Yang W, Sun J, Chen J, Li F, Disclosing Potential Therapeutic Targets Associated With Osimertinib Resistance in the Non-small Cell Lung Cancer Cell Line H1975. Anticancer Res, 43(12):5459-5474(2023) [pubmed]

submitter keyword: Osimertinib, resistant, NSCLC, omics analysis, H1975/OSI

Xuexia Tong
contact affiliation	General Hospital of Ningxia Medical University
contact email	xuexiatong@hotmail.com
lab head
Xuexia Tong
contact affiliation	General Hospital of Ningxia Medical University
contact email	xuexiatong@hotmail.com
dataset submitter

iProX dataset URI