PXD043791

PXD043791 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Suppression of mitochondrial complex 1 in Drosophila melanogaster
Description	Aberrant mitochondrial function has been associated with an increasingly large number of human disease states. Observations from in vivo models where mitochondrial function is altered suggest that adaptations to mitochondrial dysfunction may underpin disease pathology. We hypothesized that the severity of these maladaptations could be shaped by the plasticity of the system when mitochondrial dysfunction manifests. To investigate this, we have used inducible fly models of mitochondrial complex I (CI) dysfunction to reduce mitochondrial function at two stages of the fly lifecycle, from early development and adult eclosion.
HostingRepository	PRIDE
AnnounceDate	2025-01-15
AnnouncementXML	Submission_2025-01-15_00:41:38.326.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yizhou Yu
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-14 11:17:43	ID requested
⏵ 1	2025-01-15 00:41:38	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: development,Drosophila melanogaster, mitochondrial complex 1

submitter keyword: development,Drosophila melanogaster, mitochondrial complex 1

Contact List

Luis Miguel Martins
contact affiliation	MRC Toxicology Unit, University of Cambridge
contact email	martins.lmiguel@gmail.com
lab head
Yizhou Yu
contact affiliation	University of Cambridge
contact email	yizhou0421@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD043791
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD043791

PRIDE project URI

Repository Record List

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