PXD043781
PXD043781 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Targeting USP8 inhibits O-GlcNAcylation of SLC7A11 to promote ferroptosis of hepatocellular carcinoma via stabilization of OGT |
| Description | To explore the proteins that are potentially regulated by USP8, we performed immunoprecipitation-based mass spectrometry (IP-MS) following ectopic expression of Flag-USP8 and immunoprecipitation. We noticed that the O-Linked N-Acetylglucosamine (GlcNAc) Transferase (OGT) was immunoprecipitated by USP8 |
| HostingRepository | iProX |
| AnnounceDate | 2023-07-10 |
| AnnouncementXML | Submission_2024-05-27_21:30:26.202.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jianing Tang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | phosphorylated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-07-14 00:24:48 | ID requested | |
| 1 | 2023-07-14 00:25:09 | announced | |
| ⏵ 2 | 2024-05-27 21:30:27 | announced | 2024-05-28: Update information. |
Publication List
| Tang J, Long G, Hu K, Xiao D, Liu S, Xiao L, Zhou L, Tao Y, Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT. Adv Sci (Weinh), 10(33):e2302953(2023) [pubmed] |
Keyword List
| submitter keyword: USP8, OGT, liver cancer |
Contact List
| Jianing Tang | |
|---|---|
| contact affiliation | Central South University |
| contact email | TangJN@csu.edu.cn |
| lab head | |
| Jianing Tang | |
| contact affiliation | Central South University |
| contact email | TangJN@csu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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