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PXD043748

PXD043748 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCharacterization of ZIC4 role in choroid plexus carcinoma
DescriptionZIC4 is a transcription factor related to pathways like NOTCH and Sonic Hedgehog (Shh) pathways which are involved in choroid plexus carcinoma (CPC). The current study describes the effect of ZIC4 gene re-expression on a CPC cell line proteome. We performed SILAC-based proteomics of ZIC4-transfected cells versus control cells, as well as empty vector-transfected cells versus control cells. Re-expression of ZIC4 may lead to a better understanding of global gene regulation and identify its role in CPC pathogenesis.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:51:32.945.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDina Hesham
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-07-13 03:24:43ID requested
12024-07-26 02:29:39announced
22024-10-22 06:51:33announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: LC-MSMS, CCHE-45, choroid plexus carcinoma, SILAC,ZIC4
Contact List
Shahenda El-Naggar
contact affiliationTumor Biology Research Program, Basic Research Unit, Research Department, Children’s Cancer Hospital in Egypt 57357, Cairo, Egypt
contact emailshahenda.elnaggar@57357.org
lab head
Dina Hesham
contact affiliationChildren's Cancer Hospital 57357 Egypt
contact emaildina.hesham139@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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