PXD043722

PXD043722 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Geographical origin and antigenicity of venom. Intraspecies proteomic and immunological analysis of Naja mossambica venom. 2DE-LC/MS approach
Description	The main objective of the project is to find the reason why antivenoms commonly used in treatments of Naja mossambica bites are not effective in Eswatini and Mozambique, whereas they exhibit normal activity in other countries of southern Africa. The main hypothesis here assumes that intra-species differences in protein composition of venoms from different part of the continent are the main cause of observed diversity in antivenom efficacy. In the course of the project, there is also a plan to identify the specific toxins that differ analyzed venoms in reactivity towards antivenom immunoglobulins.
HostingRepository	PRIDE
AnnounceDate	2024-03-15
AnnouncementXML	Submission_2024-03-15_09:09:17.701.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD043722
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Konrad Hus
SpeciesList	scientific name: Naja mossambica; NCBI TaxID: 8644;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-12 08:18:17	ID requested
⏵ 1	2024-03-15 09:09:18	announced

Publication List

10.6019/PXD043722;
10.1371/JOURNAL.PNTD.0012057;

10.6019/PXD043722;

10.1371/JOURNAL.PNTD.0012057;

Keyword List

submitter keyword: antivenom, venom, 2DE-LC/MS,Naja mossambica

submitter keyword: antivenom, venom, 2DE-LC/MS,Naja mossambica

Contact List

Aleksandra Bocian
contact affiliation	Rzeszow University of Technology
contact email	bocian@prz.edu.pl
lab head
Konrad Hus
contact affiliation	Rzeszow University of Technology
contact email	k.hus@prz.edu.pl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD043722
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD043722

PRIDE project URI

Repository Record List

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