PXD043708

PXD043708 is an original dataset announced via ProteomeXchange.

Title	Dynamic analysis of nano-protein interaction in cell transport of nano-drugs based on proximity labeling strategy
Description	We have constructed nanoparticles that can in-situ label the protein microenvironment in living cells. When the nanoparticles were exposed to cellular vesicles, hydrogen peroxide was used to initiate the labeling reaction for 1 minute. The nanoparticles could activate the biotin tag around them, and the activated biotin tag molecules would bind to the proteins around the nanoparticles, so as to obtain the protein microenvironment of the nanoparticles in the living cellular vesicles.
HostingRepository	iProX
AnnounceDate	2023-07-12
AnnouncementXML	Submission_2024-02-27_18:42:53.298.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Junji Ren
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-12 03:20:11	ID requested
1	2023-07-12 03:20:26	announced
⏵ 2	2024-02-27 18:42:54	announced	2024-02-28: Update information.

Ren J, Zhang Z, Geng S, Cheng Y, Han H, Fan Z, Dai W, Zhang H, Wang X, Zhang Q, He B, Molecular Mechanisms of Intracellular Delivery of Nanoparticles Monitored by an Enzyme-Induced Proximity Labeling. Nanomicro Lett, 16(1):103(2024) [pubmed]

submitter keyword: nano-protein interaction, proximity labeling strategy, cellular transportation

Qiang Zhang
contact affiliation	Peking University
contact email	zqdodo@bjmu.edu.cn
lab head
Junji Ren
contact affiliation	Peking University
contact email	r526963150junji@126.com
dataset submitter

iProX dataset URI