PXD043647

PXD043647 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Geographical origin and antigenicity of venom. Intraspecies proteomic and immunological analysis of Naja mossambica venom.
Description	The main objective of the project is to find the reason why antivenoms commonly used in treatments of Naja mossambica bites are not effective in Eswatini and Mozambique, whereas they exhibit normal activity in other countries of southern Africa. The main hypothesis here assumes that intra-species differences in protein composition of venoms from different part of the continent are the main cause of observed diversity in antivenom efficacy. In the course of the project, there is also a plan to identify the specific toxins that differ analyzed venoms in reactivity towards antivenom immunoglobulins.
HostingRepository	PRIDE
AnnounceDate	2024-03-15
AnnouncementXML	Submission_2024-03-15_08:58:21.467.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD043647
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Konrad Hus
SpeciesList	scientific name: Naja mossambica; NCBI TaxID: 8644;
ModificationList	methylthiolated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-10 08:51:38	ID requested
⏵ 1	2024-03-15 08:58:21	announced

Publication List

10.1371/JOURNAL.PNTD.0012057;
10.6019/PXD043647;

10.1371/JOURNAL.PNTD.0012057;

10.6019/PXD043647;

Keyword List

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: venom
Naja mossambica
LC-MS/MS
venomics
antivenoms

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: venom

Naja mossambica

LC-MS/MS

venomics

antivenoms

Contact List

Aleksandra Bocian
contact affiliation	Rzeszow University of Technology
contact email	bocian@prz.edu.pl
lab head
Konrad Hus
contact affiliation	Rzeszow University of Technology
contact email	k.hus@prz.edu.pl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD043647
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD043647

PRIDE project URI

Repository Record List

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