PXD043531 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | A deep XL-proteomic dataset of intact HEK293T cells using DSBSO |
Description | Cross-linking mass spectrometry is an emerging method to study protein-protein interactions (PPIs) in intact biological systems. Here, we optimized a workflow for gnerating high coverage maps of PPIs using the enrichable cross-linker Azide-A-DSBSO. This created one of the largest to-date XL-MS datasets, enabling structural characterization of thousands of PPIs in their intact subcellular environment. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-17 |
AnnouncementXML | Submission_2024-10-17_02:26:20.102.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Boris Bogdanow |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-07-04 05:05:09 | ID requested | |
⏵ 1 | 2024-10-17 02:26:20 | announced | |
Publication List
Keyword List
submitter keyword: Human, deep XL-MS, Cell Culture |
Contact List
Fan Liu |
contact affiliation | Leibniz-Institute for Molecular Pharmacology (FMP) |
contact email | fliu@fmp-berlin.de |
lab head | |
Boris Bogdanow |
contact affiliation | Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) |
contact email | bogdanow@fmp-berlin.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD043531
- Label: PRIDE project
- Name: A deep XL-proteomic dataset of intact HEK293T cells using DSBSO