PXD043455

PXD043455 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Neisseria meningitidis serogroup A whole cel LC-MS/MS
Description	In a comprehensive study using comparative whole genome sequencing, 100 African isolates were examined, revealing the pilin glycosylation (pgl) locus as a prominent site for recombination events. Notably, the transfer of pgl genes through lateral gene transfer occurs frequently within N. meningitidis serogroup A, leading to variations in the glycosylation patterns of pilin and other glycoproteins on the cell surface. To elucidate these differences, mass spectrometry was employed to analyze the glycan structure associated with different pgl allele types.
HostingRepository	PRIDE
AnnounceDate	2026-08-17
AnnouncementXML	Submission_2026-08-16_16:13:19.130.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Freda Jen
SpeciesList	scientific name: Neisseria meningitidis serogroup A; NCBI TaxID: NEWT:65699;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-02 21:40:16	ID requested
⏵ 1	2026-08-16 16:13:19	announced

Publication List

Jen FE, Abrahams JL, Schulz BL, Lamelas A, Pluschke G, Jennings MP, Serogroup a Meningitis Outbreaks in the African Meningitis Belt. ACS Infect Dis, 9(8):1451-1457(2023) [pubmed]
10.1021/acsinfecdis.3c00149;

Jen FE, Abrahams JL, Schulz BL, Lamelas A, Pluschke G, Jennings MP, Serogroup a Meningitis Outbreaks in the African Meningitis Belt. ACS Infect Dis, 9(8):1451-1457(2023) [pubmed]

10.1021/acsinfecdis.3c00149;

Keyword List

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: glycosylation,Neisseria meningitidis

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: glycosylation,Neisseria meningitidis

Contact List

Michael Jennings
contact affiliation	Griffith University
contact email	m.jennings@griffith.edu.au
lab head
Freda Jen
contact affiliation	Griffith University
contact email	f.jen@griffith.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD043455
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD043455

PRIDE project URI

Repository Record List

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