PXD043391

PXD043391 is an original dataset announced via ProteomeXchange.

Title	MS data for Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis
Description	Cotranslational protein folding depends on general chaperones that engage highly diverse nascent chains at the ribosomes. It is not clear how this promiscuous mechanism ensure efficient production of challenging clients such as highly expressed proteins. Here we find that the biogenesis of the abundantly expressed eukaryotic translation elongation factor 1A (eEF1A) depends on the dedicated ribosome-associated chaperone Chp1.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:45:30.011.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jany Quintana Cordero
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	No PTMs are included in the dataset
Instrument	Thermo Finnigan instrument model

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-29 04:24:40	ID requested
1	2024-06-16 01:09:00	announced
⏵ 2	2024-10-22 06:45:30	announced	2024-10-22: Updated project metadata.

Minoia M, Quintana-Cordero J, Jetzinger K, Kotan IE, Turnbull KJ, Ciccarelli M, Masser AE, Liebers D, Gouarin E, Czech M, Hauryliuk V, Bukau B, Kramer G, Andr, é, asson C, Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis. Nat Commun, 15(1):1382(2024) [pubmed]

10.1038/s41467-024-45645-w;

submitter keyword: ribosome-associated chaperone, Hsf1 activation,eEF1A biogenesis

Claes Andréasson
contact affiliation	Stockholm University
contact email	claes.andreasson@su.se
lab head
Jany Quintana Cordero
contact affiliation	Stockholm University
contact email	jany.quintanacordero@su.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD043391

PRIDE project URI

• PRIDE
  1. PXD043391
     1. Label: PRIDE project
     2. Name: MS data for Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis