PXD043391 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | MS data for Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis |
Description | Cotranslational protein folding depends on general chaperones that engage highly diverse nascent chains at the ribosomes. It is not clear how this promiscuous mechanism ensure efficient production of challenging clients such as highly expressed proteins. Here we find that the biogenesis of the abundantly expressed eukaryotic translation elongation factor 1A (eEF1A) depends on the dedicated ribosome-associated chaperone Chp1. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:45:30.011.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jany Quintana Cordero |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | No PTMs are included in the dataset |
Instrument | Thermo Finnigan instrument model |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-06-29 04:24:40 | ID requested | |
1 | 2024-06-16 01:09:00 | announced | |
⏵ 2 | 2024-10-22 06:45:30 | announced | 2024-10-22: Updated project metadata. |
Publication List
Minoia M, Quintana-Cordero J, Jetzinger K, Kotan IE, Turnbull KJ, Ciccarelli M, Masser AE, Liebers D, Gouarin E, Czech M, Hauryliuk V, Bukau B, Kramer G, Andr, é, asson C, Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis. Nat Commun, 15(1):1382(2024) [pubmed] |
10.1038/s41467-024-45645-w; |
Keyword List
submitter keyword: ribosome-associated chaperone, Hsf1 activation,eEF1A biogenesis |
Contact List
Claes Andréasson |
contact affiliation | Stockholm University |
contact email | claes.andreasson@su.se |
lab head | |
Jany Quintana Cordero |
contact affiliation | Stockholm University |
contact email | jany.quintanacordero@su.se |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/06/PXD043391 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD043391
- Label: PRIDE project
- Name: MS data for Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis