PXD043230

PXD043230 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Chemical proteomics reveals the target landscape of 1,000 kinase inhibitor tool compounds
Description	Here, we profiled the targets of 1,184 compounds from drug discovery projects in lysates of cancer cell lines using the Kinobeads approach. The resulting 500,000 compound-target interactions are available in ProteomicsDB and we exemplify how this molecular resource may be used for research. We anticipate that this molecular resource will aid drug discovery and chemical biology.
HostingRepository	MassIVE
AnnounceDate	2023-09-04
AnnouncementXML	Submission_2023-09-04_16:27:17.466.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Maria Reinecke
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-23 01:31:12	ID requested
⏵ 1	2023-09-04 16:27:17	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Kinase inhibitors, Chemical proteomics, LC-MS/MS, Mass spectrometry, Selectivity

submitter keyword: Kinase inhibitors, Chemical proteomics, LC-MS/MS, Mass spectrometry, Selectivity

Contact List

Bernhard Kuster
contact affiliation	Technical University of Munich, Chair of Proteomics and Bioanalytics
contact email	kuster@tum.de
lab head
Maria Reinecke
contact affiliation	TU Muenchen
contact email	maria.reinecke@tum.de
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000092248/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000092248/