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PXD043225

PXD043225 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInteractors of USP7-TRAF domain in rat neurons
DescriptionUSP7 protein has a TRAF domain near the N-terminus, which has been reported to bind to many substrates of USP7 in cancer cells. Here we looked for interactors of this USP7-TRAF domain in primary rat neurons. We expressed and immunprecipitated the FLAG-tagged USP7-TRAF domain in neurons. We also used the binding-deficient mutant TRAF RDW as negative control. The immunoprecipitated USP7-TRAF along with its interactors were profiled with LC-MS/MS.
HostingRepositoryPRIDE
AnnounceDate2025-02-24
AnnouncementXMLSubmission_2025-02-24_13:44:56.272.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHao Chen
SpeciesList scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-06-22 23:16:01ID requested
12025-02-24 13:44:56announced
Publication List
10.1016/J.CELREP.2025.115231;
Keyword List
submitter keyword: Neuron, immunoprecipitation, USP7
Contact List
Albert H. Kim
contact affiliationDepartment of Neural Surgery, Washington University School of Medicine in St. Louis
contact emailalberthkim@wustl.edu
lab head
Hao Chen
contact affiliationWashington University in St. Louis
contact emailchenhao@wustl.edu
dataset submitter
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Dataset FTP location
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PRIDE project URI
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