PXD043225

PXD043225 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Interactors of USP7-TRAF domain in rat neurons
Description	USP7 protein has a TRAF domain near the N-terminus, which has been reported to bind to many substrates of USP7 in cancer cells. Here we looked for interactors of this USP7-TRAF domain in primary rat neurons. We expressed and immunprecipitated the FLAG-tagged USP7-TRAF domain in neurons. We also used the binding-deficient mutant TRAF RDW as negative control. The immunoprecipitated USP7-TRAF along with its interactors were profiled with LC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2025-02-24
AnnouncementXML	Submission_2025-02-24_13:44:56.272.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hao Chen
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-22 23:16:01	ID requested
⏵ 1	2025-02-24 13:44:56	announced

Publication List

10.1016/J.CELREP.2025.115231;

10.1016/J.CELREP.2025.115231;

Keyword List

submitter keyword: Neuron, immunoprecipitation, USP7

submitter keyword: Neuron, immunoprecipitation, USP7

Contact List

Albert H. Kim
contact affiliation	Department of Neural Surgery, Washington University School of Medicine in St. Louis
contact email	alberthkim@wustl.edu
lab head
Hao Chen
contact affiliation	Washington University in St. Louis
contact email	chenhao@wustl.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD043225
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD043225

PRIDE project URI

Repository Record List

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