⮝ Full datasets listing

PXD043196

PXD043196 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleWidespread Involvement of Acetylation in the Retinal Metabolism of Form-Deprivation Myopia in Guinea Pigs
DescriptionMyopia has become the major cause of visual impairment worldwide. Although the pathogenesis of myopia remains controversial, proteomics studies suggest that dysregulation of retinal metabolism is potentially involved in the pathology of myopia. Lysine acetylation of proteins plays a key role in regulating cellular metabolism, but little is known about its role in the form-deprived myopic retina. In this study, we performed acetylation proteomic analysis of the retinas of form-deprived myopic guinea pigs and found downregulated levels of acetylation of metabolism-critical enzymes in the retina. As the first report on retinal acetylation in myopic eyes, this study provides a reliable basis for further studies on retinal acetylation in myopic eyes
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:53:39.283.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterjiaojiao Feng
SpeciesList scientific name: Cavia porcellus (Guinea pig); NCBI TaxID: 10141;
ModificationListacetylated residue
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-06-21 22:46:31ID requested
12023-07-12 01:23:42announced
22023-11-14 07:09:27announced2023-11-14: Updated project metadata.
32024-10-22 05:53:39announced2024-10-22: Updated project metadata.
Publication List
10.1021/ACSOMEGA.3C02219;
Keyword List
submitter keyword: form-deprivation myopia
retina
lysine acetylation
glycolysis
Contact List
Hongsheng Bi
contact affiliationAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine
contact emailhongshengbi1@163.com
lab head
jiaojiao Feng
contact affiliationShandong University of Traditional Chinese Medicine
contact emailszyykxfjj2021@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD043196
PRIDE project URI
Repository Record List
[ + ]