PXD043101

PXD043101 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	PRMT-7/PRMT7 activates HLH-30/TFEB to guard plasma membrane integrity compromised by pore-forming toxins
Description	This research reveals that protein arginine methyltransferase-7 (PRMT-7) is indispensable to the nuclear transactivation of HLH-30. We demonstrated that PRMT-7 participates in the methylation of HLH-30 on its Rag complex binding domain to facilitate its nuclear localization. Moreover, we showed that PRMT7 is evolutionarily conserved to regulate TFEB cellular localization and repair plasma damage caused by PFTs in human intestinal cells.
HostingRepository	PRIDE
AnnounceDate	2024-01-26
AnnouncementXML	Submission_2024-01-25_22:50:29.877.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hui-Chen Hsieh
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	monomethylated residue; phosphorylated residue
Instrument	impact HD

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-19 07:40:36	ID requested
⏵ 1	2024-01-25 22:50:30	announced

Publication List

10.1080/15548627.2024.2306655;

10.1080/15548627.2024.2306655;

Keyword List

submitter keyword: MS/MS,C. elegans, arginine methylation

submitter keyword: MS/MS,C. elegans, arginine methylation

Contact List

Chang-Shi Chen
contact affiliation	Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
contact email	cschen@mail.ncku.edu.tw
lab head
Hui-Chen Hsieh
contact affiliation	National Cheng Kung University
contact email	s16074055@gs.ncku.edu.tw
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD043101
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD043101

PRIDE project URI

Repository Record List

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