PXD043055

PXD043055 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	WNT2B is required for development and function of human intestine
Description	The experiment goal was to identify differentially expressed proteins associated with WNT2B mutation p.R69* in human intestinal epithelia. Skin fibroblasts from a patient with the mutation were used to establish human intestinal organoids (HIOs). The hESC H1 cell line was used to generate wild-type WNT2B HIOs for comparison. The HIOs were transplanted into mice to promote maturation for 8 weeks, followed by dissection and crypt isolation to seed ex vivo epithelial (enteroid) cultures. The enteroid cultures were harvested for analysis by tandem mass tag spectrometry.
HostingRepository	MassIVE
AnnounceDate	2023-06-16
AnnouncementXML	Submission_2023-06-16_07:12:55.715.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jennifer Foulke-Abel
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	TMTpro; Carbamidomethyl
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-16 06:22:38	ID requested
⏵ 1	2023-06-16 07:12:56	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: WNT2B intestinal organoid enteroid epithelia

submitter keyword: WNT2B intestinal organoid enteroid epithelia

Contact List

Jennifer Foulke-Abel
contact affiliation	Johns Hopkins University School of Medicine
contact email	jfoulke@jhmi.edu
lab head
Jennifer Foulke-Abel
contact affiliation	Johns Hopkins University School of Medicine
contact email	jfoulke@jhmi.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000092189/