PXD043039

PXD043039 is an original dataset announced via ProteomeXchange.

Title	Comparative proteomic analysis identifies differentially expressed proteins associated with meiotic arrest in cattle-yak hybrids
Description	Comparative proteomic analysis identified a total of 452 differentially abundant proteins (DAPs) in the fluorescence-activated cell sorting (FACS) isolated spermatocytes from 12-month-old yak and cattleyak. 291 proteins were only identified in yak spermatocytes. Gene Ontology analysis revealed that the downregulated DAPs were mostly enriched in the cellular response to DNA damage stimulus and double-strand break (DSB) repair via break-induced replication, while the proteins specific for yak were related to cell division and cycle, spermatogenesis, and negative regulation of the extrinsic apoptotic signaling pathway.
HostingRepository	iProX
AnnounceDate	2023-03-21
AnnouncementXML	Submission_2023-06-15_19:18:23.381.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shixin Wu
SpeciesList	scientific name: Bos mutus; NCBI TaxID: 72004;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-15 19:18:15	ID requested
⏵ 1	2023-06-15 19:18:23	announced

Dataset with its publication pending

submitter keyword: Protein profile, spermatocytes of cattle-yak

Qien Yang
contact affiliation	Northwest Institute of Plateau Biology, Chinese Academy of Sciences
contact email	yangqien@nwipb.cas.cn
lab head
Shixin Wu
contact affiliation	Northwest Institute of Plateau Biology, Chinese Academy of Sciences
contact email	wusx@nwipb.cas.cn
dataset submitter

iProX dataset URI