PXD042975

PXD042975 is an original dataset announced via ProteomeXchange.

Title	TMT Multiplexing-Based Quantitative Analysis of Pathogenic Th2 Proteomes.
Description	To investigate the regulation of pathogenic Th2 (pTh2) cells and the role of histone deacetylase 1 (HDAC1) in the respective processes, we used a new in vitro protocol for generating pTh2 cells and performed qunatitative mass spectrometry analysis based on TMTpro 16plex multiplexing to analyze proteomes. We profiled classical Th2 and pTh2 cells from wild type (WT) mice and mice with a T cell-specific deletion of HDAC1 (HDAC1-cKO).
HostingRepository	PRIDE
AnnounceDate	2025-02-20
AnnouncementXML	Submission_2025-02-20_00:10:17.764.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wolfgang Reiter
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-14 02:28:53	ID requested
⏵ 1	2025-02-20 00:10:18	announced

Dataset with its publication pending

submitter keyword: TMTpro 16plex, pathogenic Th2 cells, Mus musculus,Th2 cells

Dr. Markus Hartl
contact affiliation	Mass Spectrometry Facility, Max Perutz Labs Vienna, University of Vienna, Vienna Biocenter, Dr.-Bohr-Gasse 7, 1030 Vienna
contact email	markus.hartl@univie.ac.at
lab head
Wolfgang Reiter
contact affiliation	Mass Spectrometry Facility, Max Perutz Labs Vienna, University of Vienna, Vienna Biocenter, Dr.-Bohr-Gasse 7, 1030 Vienna
contact email	wolfgang.l.reiter@univie.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD042975

PRIDE project URI

• PRIDE
  1. PXD042975
     1. Label: PRIDE project
     2. Name: TMT Multiplexing-Based Quantitative Analysis of Pathogenic Th2 Proteomes.