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PXD042975

PXD042975 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTMT Multiplexing-Based Quantitative Analysis of Pathogenic Th2 Proteomes.
DescriptionTo investigate the regulation of pathogenic Th2 (pTh2) cells and the role of histone deacetylase 1 (HDAC1) in the respective processes, we used a new in vitro protocol for generating pTh2 cells and performed qunatitative mass spectrometry analysis based on TMTpro 16plex multiplexing to analyze proteomes. We profiled classical Th2 and pTh2 cells from wild type (WT) mice and mice with a T cell-specific deletion of HDAC1 (HDAC1-cKO).
HostingRepositoryPRIDE
AnnounceDate2025-02-20
AnnouncementXMLSubmission_2025-02-20_00:10:17.764.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterWolfgang Reiter
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-06-14 02:28:53ID requested
12025-02-20 00:10:18announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: TMTpro 16plex, pathogenic Th2 cells, Mus musculus,Th2 cells
Contact List
Dr. Markus Hartl
contact affiliationMass Spectrometry Facility, Max Perutz Labs Vienna, University of Vienna, Vienna Biocenter, Dr.-Bohr-Gasse 7, 1030 Vienna
contact emailmarkus.hartl@univie.ac.at
lab head
Wolfgang Reiter
contact affiliationMass Spectrometry Facility, Max Perutz Labs Vienna, University of Vienna, Vienna Biocenter, Dr.-Bohr-Gasse 7, 1030 Vienna
contact emailwolfgang.l.reiter@univie.ac.at
dataset submitter
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Dataset FTP location
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Repository Record List
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