PXD042959

PXD042959 is an original dataset announced via ProteomeXchange.

Title	Functional Classification of DDOST Variants of Uncertain Clinical Significance in Congenital Disorders of Glycosylation
Description	identification of OST48 as a transient inetactor of lysyl oxidase (LOX)OST48 is a non catalytic component of the OST complex which transfers glycans to substrate proteins. OST48 is encoded by DDOST.43 cariants of DDOST are described in CDG patients
HostingRepository	PRIDE
AnnounceDate	2023-10-18
AnnouncementXML	Submission_2023-10-17_23:49:07.201.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD042959
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	DuncanSmith
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-13 15:54:57	ID requested
⏵ 1	2023-10-17 23:49:07	announced

10.6019/PXD042959;

submitter keyword: Congeniatal disorders of glycosylation, lysl oxidase, functional assay, APEX2 proximity labelling

Duncan LeonardSmith
contact affiliation	CRUK Manchester Institute, University of Manchester
contact email	duncan.smith@cruk.manchester.ac.uk
lab head
DuncanSmith
contact affiliation	CRUK Manchester Institute, University of Manchester
contact email	duncan.smith@cruk.manchester.ac.uk
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD042959
     1. Label: PRIDE project
     2. Name: Functional Classification of DDOST Variants of Uncertain Clinical Significance in Congenital Disorders of Glycosylation