PXD042952

PXD042952 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Intracellular Proteomics and Extracellular Vesiculomics as a Metric of Disease Recapitulation in 3D Bioprinted Aortic Valve Arrays
Description	We present a novel bioprinted array model of calcific aortic valve disease. Additionally, we utilize LC-MS/MS based proteomics to characterize cellular and extracellular vesicle proteomics of valve disease models compared to native diseased tissue as a metric of disease recapitulation.
HostingRepository	PRIDE
AnnounceDate	2024-02-26
AnnouncementXML	Submission_2024-02-26_14:48:26.144.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD042952
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Cassandra Clift
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-13 12:16:43	ID requested
⏵ 1	2024-02-26 14:48:26	announced

Publication List

10.6019/PXD042952;
10.1126/SCIADV.ADJ9793;

10.6019/PXD042952;

10.1126/SCIADV.ADJ9793;

Keyword List

submitter keyword: Calcification, Extracellular Vesicles,Proteomics, Bioprinting, Hydrogel, Aortic Valve

submitter keyword: Calcification, Extracellular Vesicles,Proteomics, Bioprinting, Hydrogel, Aortic Valve

Contact List

Elena Aikawa
contact affiliation	Center for Interdisciplinary Cardiovascular Sciences, Cardiovascular Division, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston MA USA
contact email	eaikawa@bwh.harvard.edu
lab head
Cassandra Clift
contact affiliation	Harvard Medical School, Brigham and Women's Hospital
contact email	cliftc@musc.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/02/PXD042952
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/02/PXD042952

PRIDE project URI

Repository Record List

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