PXD042934

PXD042934 is an original dataset announced via ProteomeXchange.

Title	Regulation of human granulosa cells by oxygen
Description	Human granulosa cells (GCs), obtained during medical reproductive procedures can be cultured and are a cellular model for the human ovary. Oxygen concentrations are regarded as important regulators of GCs. We examined consequences of low (1%) O2 versus standard atmospheric conditions in cultured human GCs for four days. A proteomic analysis of three pools of human GCs was performed. While differences between the pools of GCs were noted, the abundance of 133 proteins was significantly increased in hypoxia in all samples, whereas the abundance of 391 proteins was decreased.
HostingRepository	PRIDE
AnnounceDate	2023-12-20
AnnouncementXML	Submission_2023-12-20_07:37:09.352.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ignasi Forne
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-13 00:32:00	ID requested
⏵ 1	2023-12-20 07:37:09	announced

10.1093/MOLEHR/GAAD049;

submitter keyword: Ovary, proteomic analysis, Inflammation, Hypoxia

Prof. Dr. med. Artur Mayerhofer
contact affiliation	Department for Cell Biology BioMedizinisches Centrum - BMC LMU Muenchen, Med. Faculty Großhaderner Straße 9 82152 Planegg-Martinsried
contact email	mayerhofer@lrz.uni-muenchen.de
lab head
Ignasi Forne
contact affiliation	Biomedical Center-LMU
contact email	ignasi.forne@lrz.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD042934

PRIDE project URI

• PRIDE
  1. PXD042934
     1. Label: PRIDE project
     2. Name: Regulation of human granulosa cells by oxygen