PXD042911

PXD042911 is an original dataset announced via ProteomeXchange.

Title	Intracellular zinc chaperones in plants
Description	Metal availability is tightly regulated within cells through metal homeostasis to prevent cytotoxicity from excess and protein inactivity from deficiency. Limited bioavailability of essential metals in soil can negatively impact crop health and yield. A plant zinc (Zn)-homeostatic mechanism involving Zn transferases has been discovered, which plays a crucial role in delivering zinc to vital zinc-dependent proteins, particularly under zinc limitation. This study focused on investigating the effects of loss of AtZNG1 (AT1G26520), a key component of this mechanism, on growth, transcriptome, and proteome in Arabidopsis thaliana during zinc deficiency. The findings from multi-omics analyses highlight the broad consequences of this mechanism's disruption. The goal of this experiment wass to identify differentially abundant proteins in A.thaliana root tissue upon Zn withdrawal, in S999 zng1 mutant cells and wild-type control.
HostingRepository	PRIDE
AnnounceDate	2025-08-21
AnnouncementXML	Submission_2025-08-21_04:44:33.380.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Paolo Cifani
SpeciesList	scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationList	monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-12 05:56:03	ID requested
⏵ 1	2025-08-21 04:44:33	announced

Dataset with its publication pending

submitter keyword: A.thaliana root TMT16plex proteomics chaperones zinc

Paolo Cifani
contact affiliation	Mass Spectrometry Shared Resource, Cold Spring Harbor Laboratory
contact email	cifani@cshl.edu
lab head
Paolo Cifani
contact affiliation	Cold Spring Harbor Laboratory
contact email	cshl.mass.spec@gmail.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD042911
     1. Label: PRIDE project
     2. Name: Intracellular zinc chaperones in plants