PXD042793

PXD042793 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Vitamin C (ascorbate) modulates the levels of several proteins in the spleen of mice
Description	In the present study, we used the Gulo-/- female and male mice model which depends entirely on ascorbate derived from the diet. Importantly, the levels of ascorbate found in the serum of Gulo-/- mice reflect the amounts of ascorbate provided in drinking water. We tested different concentrations of ascorbate ranging from 0 to 0.4 % (w/v) ascorbate, added into drinking water, until the age of four months. We performed label-free Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) global quantitative proteomic profiling to identify and quantify proteins in whole spleen extracts from our different ascorbate treated cohorts of Gulo-/- females and males.
HostingRepository	MassIVE
AnnounceDate	2024-09-30
AnnouncementXML	Submission_2024-09-30_07:43:21.721.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michel Lebel
SpeciesList	scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationList	4-hydroxy-L-proline
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-07 06:33:37	ID requested
⏵ 1	2024-09-30 07:43:22	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Vitamin C, ascorbaye, gulonolactone oxidase, mass spectrometry, spleen, mouse

submitter keyword: Vitamin C, ascorbaye, gulonolactone oxidase, mass spectrometry, spleen, mouse

Contact List

Michel Lebel
contact affiliation	Centre Hospitalier Universite Laval
contact email	michel.lebel@crchudequebec.ulaval.ca
lab head
Michel Lebel
contact affiliation	CHudeQuebe
contact email	michel.lebel@crchudequebec.ulaval.ca
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v05/MSV000092120/