PXD042606

PXD042606 is an original dataset announced via ProteomeXchange.

Title	Involvement of the microenvironment in the VC-Resist glioblastoma cells
Description	In order to understand which molecular mechanisms are involved in radiation resistance and tumor propagation of glioblastoma, our laboratory has developed in-vitro models capable of mimicking the perivascular niche. Indeed, our laboratory hypothesizes that this niche is essential for glioblastoma cells to acquire a radioresistant character. That is why we are considering culturing our glioblastoma cells (GL261 cells) with the factors secreted by the perivascular niche (conditioned medium of mouse brain blood vessels) in order to study which phosphoproteins are activated in the presence of these factors. In parallel, a RNA sequencing analysis was carried out
HostingRepository	PRIDE
AnnounceDate	2024-01-23
AnnouncementXML	Submission_2024-01-23_12:34:57.787.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Vanessa Masson
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Eclipse; Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-01 03:14:16	ID requested
⏵ 1	2024-01-23 12:34:58	announced

Dataset with its publication pending

submitter keyword: perivasculaire niche, therapy, phosphoproteins,resistance

Damarys Loew
contact affiliation	Head of the Curie Institute Mass Spectrometry Platform
contact email	damarys.loew@curie.fr
lab head
Vanessa Masson
contact affiliation	Institut Curie - Centre de Recherche
contact email	vanessa.masson@curie.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD042606

PRIDE project URI

• PRIDE
  1. PXD042606
     1. Label: PRIDE project
     2. Name: Involvement of the microenvironment in the VC-Resist glioblastoma cells