PXD042505
PXD042505 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Target Carboxylates cross-linker in Proteins for Cross-linking Mass Spectrometry |
| Description | Acidic residues (Asp and Glu) have a high prevalence on protein surfaces, but cross-linking reactions targeting these residues are limited. Existing methods either require high-concentration coupling reagents or have low structural compatibility. Here we extended our previously reported “plant-and-cast” strategy to develop two heterobifunctional cross-linkers DE1 and OPAAZ. These cross-linking reaction proceeds at neutral pH and room temperature without coupling reagents. |
| HostingRepository | iProX |
| AnnounceDate | 2023-05-25 |
| AnnouncementXML | Submission_2023-11-02_19:00:23.542.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Qingqing Liao |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | oxidation |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-05-25 19:45:09 | ID requested | |
| ⏵ 1 | 2023-11-02 19:00:23 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: protein-protein interactions, chemical cross-linker, XL-MS |
Contact List
| Bing Yang | |
|---|---|
| contact affiliation | Zhejiang University |
| contact email | bingyang@zju.edu.cn |
| lab head | |
| Qingqing Liao | |
| contact affiliation | Zhejiang University |
| contact email | 11907049@zju.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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