PXD042462
PXD042462 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SIRT1/Autophagy axis Ignites Inflammatory in Hepatocarcinogenesis |
| Description | We show that SIRT1 mRNA level, as well as protein level, is overexpressed in HCC samples, and high expression of SIRT1 is remarkedly associated with advanced stage and poor prognosis. Proteomics analysis is performed on SIRT1-overexpressed HepG2 cells and the results reveal that the differently expressed proteins (DEPs) are significantly enriched in autophagy, revealing the pro-effect of SIRT1 on autophagy. |
| HostingRepository | iProX |
| AnnounceDate | 2023-05-24 |
| AnnouncementXML | Submission_2023-05-23_23:33:17.784.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jingbo Qie |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-05-23 23:33:06 | ID requested | |
| ⏵ 1 | 2023-05-23 23:33:18 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Sirt1, Autophagy, HCC, inflammatory, immunology |
Contact List
| Zhenbin Ding | |
|---|---|
| contact affiliation | Fudan University |
| contact email | 13636388572@163.com |
| lab head | |
| Jingbo Qie | |
| contact affiliation | Fudan University |
| contact email | qiejingbo@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
to receive all new ProteomeXchange dataset release announcements!
