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PXD042415

PXD042415 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePrognostic significance of the proteome profile of well differentiated papillary thyroid carcinoma
DescriptionThis research will evaluate the role of tissue proteome profile in regional metastatic disease. Considering that one of the main factors of survival in patients with papillary thyroid carcinoma is the presence of regional or distant metastatic disease, this research will focus on the difference in the proteome profiles between papillary thyroid carcinomas which had regional metastatic disease present at the time of surgery, and ones that did not have regional metastatic disease in neck lymph nodes at the time of surgery. In this study, 10 samples of papillary thyroid carcinomas without regional metastatic disease and 10 samples of well-differentiated papillary thyroid carcinomas with regional metastatic disease will be analyzed. The goal of this research is to try to identifiy certain differences in tissue proteomic profiles of papillary thyroid carcinoma depending on the presence of regional metastatic disease in neck lymph nodes.
HostingRepositoryPRIDE
AnnounceDate2025-07-21
AnnouncementXMLSubmission_2025-07-20_16:36:31.488.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMarko Mocibob
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-23 01:24:36ID requested
12025-07-20 16:36:32announced
Publication List
Matovinovic F, Novak R, Hrkac S, Salai G, Mocibob M, Pranjic M, Ko, Å¡, ec A, Bedekovic V, Grgurevic L, In search of new stratification strategies: tissue proteomic profiling of papillary thyroid microcarcinoma in patients with localized disease and lateral neck metastases. J Cancer Res Clin Oncol, 149(19):17405-17417(2023) [pubmed]
10.1007/s00432-023-05452-0;
Keyword List
submitter keyword: proteomics
papillary thyroid carcinoma
metastasis
Contact List
Lovorka Grgurević
contact affiliationCenter for Translational and Clinical Research, Department of Proteomics, School of Medicine, University of Zagreb, Zagreb, Croatia
contact emaillovorka.grgurevic@mef.hr
lab head
Marko Mocibob
contact affiliationUniversity of Zagreb, Faculty of Science
contact emailmocibob@chem.pmf.hr
dataset submitter
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Dataset FTP location
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