PXD042415 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Prognostic significance of the proteome profile of well differentiated papillary thyroid carcinoma |
| Description | This research will evaluate the role of tissue proteome profile in regional metastatic disease. Considering that one of the main factors of survival in patients with papillary thyroid carcinoma is the presence of regional or distant metastatic disease, this research will focus on the difference in the proteome profiles between papillary thyroid carcinomas which had regional metastatic disease present at the time of surgery, and ones that did not have regional metastatic disease in neck lymph nodes at the time of surgery. In this study, 10 samples of papillary thyroid carcinomas without regional metastatic disease and 10 samples of well-differentiated papillary thyroid carcinomas with regional metastatic disease will be analyzed. The goal of this research is to try to identifiy certain differences in tissue proteomic profiles of papillary thyroid carcinoma depending on the presence of regional metastatic disease in neck lymph nodes. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-07-21 |
| AnnouncementXML | Submission_2025-07-20_16:36:31.488.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Marko Mocibob |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2023-05-23 01:24:36 | ID requested | |
| ⏵ 1 | 2025-07-20 16:36:32 | announced | |
Publication List
| Matovinovic F, Novak R, Hrkac S, Salai G, Mocibob M, Pranjic M, Ko, Å¡, ec A, Bedekovic V, Grgurevic L, In search of new stratification strategies: tissue proteomic profiling of papillary thyroid microcarcinoma in patients with localized disease and lateral neck metastases. J Cancer Res Clin Oncol, 149(19):17405-17417(2023) [pubmed] |
| 10.1007/s00432-023-05452-0; |
Keyword List
| submitter keyword: proteomics |
| papillary thyroid carcinoma |
| metastasis |
Contact List
| Lovorka Grgurević |
| contact affiliation | Center for Translational and Clinical Research, Department of Proteomics, School of Medicine, University of Zagreb, Zagreb, Croatia |
| contact email | lovorka.grgurevic@mef.hr |
| lab head | |
| Marko Mocibob |
| contact affiliation | University of Zagreb, Faculty of Science |
| contact email | mocibob@chem.pmf.hr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042415
- Label: PRIDE project
- Name: Prognostic significance of the proteome profile of well differentiated papillary thyroid carcinoma