PXD042365 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Secretome profiling of Artemisia absinthium extract loaded polymeric nanoparticles-treated MCF-7 and MDA MB-231 cell lines. |
| Description | Temperature and pH-sensitive, self-assembled polymeric nanoparticles, made of N-isopropyl acrylamide (NIPAAM), N-vinyl pyrrolidone (VP), and acrylic acid (AA) are biocompatible and have been used in the past with several drugs for site-specific delivery of different formulations. In the present study, the nano LC-MS/MS proteomic approach was employed to compare the secretome of Artemisia absinthium extract loaded polymeric nanoparticles-treated MCF-7 and MDA MB-231 cell lines targeted against the tumor microenvironment and comparison with corresponding untreated cell lines as a control to identify potential therapeutic targets and easily-accessible biomarkers among differentially expressed secretory proteins. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-10-22 |
| AnnouncementXML | Submission_2024-10-22_06:02:03.592.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | SAIMA WAJID |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2023-05-20 03:04:02 | ID requested | |
| 1 | 2023-08-29 04:30:47 | announced | |
| 2 | 2023-11-14 07:54:33 | announced | 2023-11-14: Updated project metadata. |
| ⏵ 3 | 2024-10-22 06:02:04 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
| submitter keyword: Artemisia absinthium, MDA MB-231, Polymeric nanoparticles,MCF-7, LC-MS/MS |
Contact List
| Saima Wajid |
| contact affiliation | Department of Biotechnology, School of Chemical & Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India |
| contact email | swajid@jamiahamdard.ac.in |
| lab head | |
| SAIMA WAJID |
| contact affiliation | Department of Biotechnology, School of Chemical & Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062. |
| contact email | swajid@jamiahamdard.ac.in |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD042365 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042365
- Label: PRIDE project
- Name: Secretome profiling of Artemisia absinthium extract loaded polymeric nanoparticles-treated MCF-7 and MDA MB-231 cell lines.