PXD042341

PXD042341 is an original dataset announced via ProteomeXchange.

Title	Proteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (UBE2Q1, UBE2QL1, UBER, UBE2S).Proteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (Ctrl, CtrlHS, E2poolRNAi, E2poolRNAiHS)
Description	The project goal is to identify the proteins that are regulated with loss of the E2 enzymes. In this study E2poolRNAi, E2poolRNAiHS were investigated.
HostingRepository	PRIDE
AnnounceDate	2024-01-30
AnnouncementXML	Submission_2024-01-30_02:46:20.882.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Vishwajeeth Pagala
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-18 12:43:08	ID requested
⏵ 1	2024-01-30 02:46:21	announced

10.1038/s41467-023-43262-7;

Hunt LC, Pagala V, Stephan A, Xie B, Kodali K, Kavdia K, Wang YD, Shirinifard A, Curley M, Graca FA, Fu Y, Poudel S, Li Y, Wang X, Tan H, Peng J, Demontis F, An adaptive stress response that confers cellular resilience to decreased ubiquitination. Nat Commun, 14(1):7348(2023) [pubmed]

submitter keyword: UBA1

E2 ubiquitin-conjugating enzymes

ubiquitin

human cells

Fabio Demontis
contact affiliation	Associate Member Developmental Neurobiology St. Jude Children's Research Hospital
contact email	fabio.demontis@stjude.org
lab head
Vishwajeeth Pagala
contact affiliation	St. Jude Children's Research Hospital
contact email	vishwajeeth.pagala@stjude.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD042341

PRIDE project URI

• PRIDE
  1. PXD042341
     1. Label: PRIDE project
     2. Name: Proteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (UBE2Q1, UBE2QL1, UBER, UBE2S).Proteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (Ctrl, CtrlHS, E2poolRNAi, E2poolRNAiHS)