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PXD042341

PXD042341 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (UBE2Q1, UBE2QL1, UBER, UBE2S).Proteomic changes induced by knockdown of UBA1 and of E2 ubiquitin-conjugating enzymes in human HEK293 cells (Ctrl, CtrlHS, E2poolRNAi, E2poolRNAiHS)
DescriptionThe project goal is to identify the proteins that are regulated with loss of the E2 enzymes. In this study E2poolRNAi, E2poolRNAiHS were investigated.
HostingRepositoryPRIDE
AnnounceDate2024-01-30
AnnouncementXMLSubmission_2024-01-30_02:46:20.882.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterVishwajeeth Pagala
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-18 12:43:08ID requested
12024-01-30 02:46:21announced
Publication List
10.1038/s41467-023-43262-7;
Hunt LC, Pagala V, Stephan A, Xie B, Kodali K, Kavdia K, Wang YD, Shirinifard A, Curley M, Graca FA, Fu Y, Poudel S, Li Y, Wang X, Tan H, Peng J, Demontis F, An adaptive stress response that confers cellular resilience to decreased ubiquitination. Nat Commun, 14(1):7348(2023) [pubmed]
Keyword List
submitter keyword: UBA1
E2 ubiquitin-conjugating enzymes
ubiquitin
human cells
Contact List
Fabio Demontis
contact affiliationAssociate Member Developmental Neurobiology St. Jude Children's Research Hospital
contact emailfabio.demontis@stjude.org
lab head
Vishwajeeth Pagala
contact affiliationSt. Jude Children's Research Hospital
contact emailvishwajeeth.pagala@stjude.org
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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