PXD042312
PXD042312 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic sequencing of atrial fibrosis rat model caused by chronic intermittent hypoxia |
| Description | This study was aimed to understand the changes of proteins occurring in atrial tissue of atrial fibrillation (AF) rat model based on proteome sequencing.SD rats were used for AF model construction by chronic intermittent hypoxia (CIH) induction. The tissue pathological changes were observed by hematoxylin-eosin staining, masson staining, and immunohistochemistry analysis of the levels of fibrosis biomarkers. Then proteome sequencing was performed on atrial fibrosis samples to identify the differentially expressed proteins (DEPs) between CIH and control groups, following by functional analysis. The protein levels of several key proteins were validated by western blotting. |
| HostingRepository | iProX |
| AnnounceDate | 2023-05-18 |
| AnnouncementXML | Submission_2023-05-18_00:47:43.129.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xue Liang |
| SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-05-18 00:47:16 | ID requested | |
| ⏵ 1 | 2023-05-18 00:47:43 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: atrial fibrillation, atrial fibrosis, protein, pathway |
Contact List
| Xue Liang | |
|---|---|
| contact affiliation | Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University |
| contact email | liangxue19841219@126.com |
| lab head | |
| Xue Liang | |
| contact affiliation | Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, the Second Hospital of Tianjin Medical University |
| contact email | liangxue19841219@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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