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PXD042310

PXD042310 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIntegrative Analysis of Transcriptome and Proteome for a new Rumen-derived Bacillus Licheniform in regulating microenvrionment Treating with Different Carbon Sources
DescriptionBacillus licheniformis (B. licheniformis) is a microorganism with a wide range of probiotic properties and applications. Isolation and identification of novel strains is a major aspect of microbial research. Besides, the role of different carbon sources affects B. licheniformis in regulating micro-environment and the mechanisms need to be further investigated. In this study, we first isolated and identified a new strain of B. licheniformis from bovine rumen fluid. Microcrystalline cellulose (MC) and cellobiose (CB) as the certain carbon sources to treat strain. Further, a combination of transcriptome and proteome analyses was used to different carbon sources effects. The results showed that B. licheniformis ABC transporter proteins, antibiotic synthesis, flagellar assembly, cellulase-related pathways and proteins were significantly up-regulated in the MC treatment compared to the CB treatment, and lactate metabolism was inhibited. In addition, MC was used as a certain carbon source to improve bacterial inhibition of B. licheniformis, its own disease resistance and to regulate the rumen micro-environment. In conclusion, our research provides a potential new probiotic for feed research and a theoretical basis for investigating the mechanisms by which bacteria respond to different carbon sources.
HostingRepositoryPRIDE
AnnounceDate2024-01-26
AnnouncementXMLSubmission_2024-01-26_09:03:58.110.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuchen Cheng
SpeciesList scientific name: Bacillus licheniformis; NCBI TaxID: 1402;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-17 22:21:04ID requested
12024-01-26 09:03:58announced
Publication List
10.3389/fmicb.2023.1238767;
Cheng Y, Zhang J, Ren W, Zhang L, Xu X, to different carbon sources. Front Microbiol, 14():1238767(2023) [pubmed]
Keyword List
submitter keyword: transcriptome,Bacillus licheniformis, different carbon sources, proteome, cows rumen fluid
Contact List
Xiaofeng Xu
contact affiliationCollege of Animal Science and Technology, Ningxia University, 489 Helanshan West Road, Xixia District, Yinchuan, Ningxia
contact emailxuxiaofengnd@126.com
lab head
Yuchen Cheng
contact affiliationDocter
contact emailYcheng95@126.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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