PXD042310

PXD042310 is an original dataset announced via ProteomeXchange.

Title	Integrative Analysis of Transcriptome and Proteome for a new Rumen-derived Bacillus Licheniform in regulating microenvrionment Treating with Different Carbon Sources
Description	Bacillus licheniformis (B. licheniformis) is a microorganism with a wide range of probiotic properties and applications. Isolation and identification of novel strains is a major aspect of microbial research. Besides, the role of different carbon sources affects B. licheniformis in regulating micro-environment and the mechanisms need to be further investigated. In this study, we first isolated and identified a new strain of B. licheniformis from bovine rumen fluid. Microcrystalline cellulose (MC) and cellobiose (CB) as the certain carbon sources to treat strain. Further, a combination of transcriptome and proteome analyses was used to different carbon sources effects. The results showed that B. licheniformis ABC transporter proteins, antibiotic synthesis, flagellar assembly, cellulase-related pathways and proteins were significantly up-regulated in the MC treatment compared to the CB treatment, and lactate metabolism was inhibited. In addition, MC was used as a certain carbon source to improve bacterial inhibition of B. licheniformis, its own disease resistance and to regulate the rumen micro-environment. In conclusion, our research provides a potential new probiotic for feed research and a theoretical basis for investigating the mechanisms by which bacteria respond to different carbon sources.
HostingRepository	PRIDE
AnnounceDate	2024-01-26
AnnouncementXML	Submission_2024-01-26_09:03:58.110.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuchen Cheng
SpeciesList	scientific name: Bacillus licheniformis; NCBI TaxID: 1402;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-17 22:21:04	ID requested
⏵ 1	2024-01-26 09:03:58	announced

10.3389/fmicb.2023.1238767;

Cheng Y, Zhang J, Ren W, Zhang L, Xu X, to different carbon sources. Front Microbiol, 14():1238767(2023) [pubmed]

submitter keyword: transcriptome,Bacillus licheniformis, different carbon sources, proteome, cows rumen fluid

Xiaofeng Xu
contact affiliation	College of Animal Science and Technology, Ningxia University, 489 Helanshan West Road, Xixia District, Yinchuan, Ningxia
contact email	xuxiaofengnd@126.com
lab head
Yuchen Cheng
contact affiliation	Docter
contact email	Ycheng95@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD042310

PRIDE project URI

• PRIDE
  1. PXD042310
     1. Label: PRIDE project
     2. Name: Integrative Analysis of Transcriptome and Proteome for a new Rumen-derived Bacillus Licheniform in regulating microenvrionment Treating with Different Carbon Sources