PXD042310 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Integrative Analysis of Transcriptome and Proteome for a new Rumen-derived Bacillus Licheniform in regulating microenvrionment Treating with Different Carbon Sources |
Description | Bacillus licheniformis (B. licheniformis) is a microorganism with a wide range of probiotic properties and applications. Isolation and identification of novel strains is a major aspect of microbial research. Besides, the role of different carbon sources affects B. licheniformis in regulating micro-environment and the mechanisms need to be further investigated. In this study, we first isolated and identified a new strain of B. licheniformis from bovine rumen fluid. Microcrystalline cellulose (MC) and cellobiose (CB) as the certain carbon sources to treat strain. Further, a combination of transcriptome and proteome analyses was used to different carbon sources effects. The results showed that B. licheniformis ABC transporter proteins, antibiotic synthesis, flagellar assembly, cellulase-related pathways and proteins were significantly up-regulated in the MC treatment compared to the CB treatment, and lactate metabolism was inhibited. In addition, MC was used as a certain carbon source to improve bacterial inhibition of B. licheniformis, its own disease resistance and to regulate the rumen micro-environment. In conclusion, our research provides a potential new probiotic for feed research and a theoretical basis for investigating the mechanisms by which bacteria respond to different carbon sources. |
HostingRepository | PRIDE |
AnnounceDate | 2024-01-26 |
AnnouncementXML | Submission_2024-01-26_09:03:58.110.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yuchen Cheng |
SpeciesList | scientific name: Bacillus licheniformis; NCBI TaxID: 1402; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-05-17 22:21:04 | ID requested | |
⏵ 1 | 2024-01-26 09:03:58 | announced | |
Publication List
Keyword List
submitter keyword: transcriptome,Bacillus licheniformis, different carbon sources, proteome, cows rumen fluid |
Contact List
Xiaofeng Xu |
contact affiliation | College of Animal Science and Technology, Ningxia University, 489 Helanshan West Road, Xixia District, Yinchuan, Ningxia |
contact email | xuxiaofengnd@126.com |
lab head | |
Yuchen Cheng |
contact affiliation | Docter |
contact email | Ycheng95@126.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042310
- Label: PRIDE project
- Name: Integrative Analysis of Transcriptome and Proteome for a new Rumen-derived Bacillus Licheniform in regulating microenvrionment Treating with Different Carbon Sources