PXD042258 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | In depth mapping of DNA-PKcs and ATM kinase signaling responses to double strand breaks. |
Description | In depth analysis of double strand break signaling was performed using mouse Pre-B cells and Human HCT116 cells. Our analysis included the induction of double strand breaks with ionizing radiation with the addition of ATM and DNA-PKcs inhibitors, alone and in combination. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-17 |
AnnouncementXML | Submission_2024-10-17_09:07:27.376.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Shannon Marshall |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | 6x(13)C; 6x(13)C |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-05-16 05:31:04 | ID requested | |
⏵ 1 | 2024-10-17 09:07:28 | announced | |
Publication List
10.1016/j.jbc.2024.107513; |
Marshall S, Navarro MVAS, Ascen, ҫ, ã, o CFR, Dibitetto D, Smolka MB, In-depth mapping of DNA-PKcs signaling uncovers noncanonical features of its kinase specificity. J Biol Chem, 300(8):107513(2024) [pubmed] |
Keyword List
submitter keyword: G1 arrest,LC-MS/MS, DNA repair, Human, Mouse, Abelson Pre-B cells, Ionizing Radiation |
Contact List
Marcus Smolka |
contact affiliation | Cornell University |
contact email | mbs266@cornell.edu |
lab head | |
Shannon Marshall |
contact affiliation | Cornell University |
contact email | sm2687@cornell.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD042258 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042258
- Label: PRIDE project
- Name: In depth mapping of DNA-PKcs and ATM kinase signaling responses to double strand breaks.