PXD042258

PXD042258 is an original dataset announced via ProteomeXchange.

Title	In depth mapping of DNA-PKcs and ATM kinase signaling responses to double strand breaks.
Description	In depth analysis of double strand break signaling was performed using mouse Pre-B cells and Human HCT116 cells. Our analysis included the induction of double strand breaks with ionizing radiation with the addition of ATM and DNA-PKcs inhibitors, alone and in combination.
HostingRepository	PRIDE
AnnounceDate	2024-10-17
AnnouncementXML	Submission_2024-10-17_09:07:27.376.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shannon Marshall
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	6x(13)C; 6x(13)C
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-16 05:31:04	ID requested
⏵ 1	2024-10-17 09:07:28	announced

10.1016/j.jbc.2024.107513;

Marshall S, Navarro MVAS, Ascen, ҫ, ã, o CFR, Dibitetto D, Smolka MB, In-depth mapping of DNA-PKcs signaling uncovers noncanonical features of its kinase specificity. J Biol Chem, 300(8):107513(2024) [pubmed]

submitter keyword: G1 arrest,LC-MS/MS, DNA repair, Human, Mouse, Abelson Pre-B cells, Ionizing Radiation

Marcus Smolka
contact affiliation	Cornell University
contact email	mbs266@cornell.edu
lab head
Shannon Marshall
contact affiliation	Cornell University
contact email	sm2687@cornell.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD042258

PRIDE project URI

• PRIDE
  1. PXD042258
     1. Label: PRIDE project
     2. Name: In depth mapping of DNA-PKcs and ATM kinase signaling responses to double strand breaks.