⮝ Full datasets listing

PXD042249

PXD042249 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative cellular proteome analysis of Fetal- and Adult-Derived MLL-Rearranged Leukemia
DescriptionInfant and adult MLL-rearranged (MLLr) leukemia represents a disease with few treatment options and a dismal prognosis. Here, we present an in-depth proteomic characterization of in utero-initiated and adult-onset MLLr leukemia in a mouse model of MLL-ENL-mediated leukemogenesis. We characterize early proteomic events of MLL-ENL-mediated transformation in fetal and adult progenitors.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:35:01.187.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSudip Ghosh
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-15 23:50:07ID requested
12024-04-02 03:00:16announced
22024-10-22 06:35:02announced2024-10-22: Updated project metadata.
Publication List
Jassinskaja M, Ghosh S, Watral J, Davoudi M, Claesson Stern M, Daher U, Eldeeb M, Zhang Q, Bryder D, Hansson J, A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived MLL-rearranged leukemia. Leukemia, 38(5):1115-1130(2024) [pubmed]
10.1038/s41375-024-02235-5;
Keyword List
submitter keyword: Adult hematopoietic progenitor, TMTpro,MLL-rearranged leukemia, Fetal hematopoietic progenitor
Contact List
Dr. Jenny Hansson
contact affiliationProteomic Hematology Department of Experimental Medical Science Lund Stem Cell Center, Lund University
contact emailjenny.hansson@med.lu.se
lab head
Sudip Ghosh
contact affiliationProteomic Hematology, Department of Experimental Medical Science, Lund Stem Cell Center, Lund University
contact emailsudip.ghosh@med.lu.se
dataset submitter
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD042249
PRIDE project URI
Repository Record List
[ + ]