PXD042162
PXD042162 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TDRD6 IP-MS data in mouse testis protein lysates |
| Description | We immunoprecipitated endogenous TDRD6 from testis protein lysates of 28-day-old wild-type mice using our home-made TDRD6 antiserum. No TDRD6 protein was identified in Tdrd6-mutant mice carrying the p.G615X (GGG to TGA) variant. Thus, Tdrd6-mutant mice were utilized as negative control. A high-throughput technology, LC/MS–MS (MS), was applied to identify the candidate interacting proteins of TDRD6. |
| HostingRepository | iProX |
| AnnounceDate | 2023-05-11 |
| AnnouncementXML | Submission_2025-06-13_00:09:54.911.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Suren Chen |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-05-11 21:37:03 | ID requested | |
| 1 | 2023-05-11 21:37:46 | announced | |
| ⏵ 2 | 2025-06-13 00:09:55 | announced | 2025-06-13: Add Publication. |
Publication List
| Bi X, Jin H, Wan F, Xia Y, Guo H, Chen S, Wang B, Loss-of-function variant in TDRD6 cause male infertility with severe oligo-astheno-teratozoospermia in human and mice. J Cell Mol Med, 28(18):e18580(2024) [pubmed] |
Keyword List
| submitter keyword: TDRD6, Spermiogenesis, Immunoprecipitation, Mass spectrometry |
Contact List
| Suren Chen | |
|---|---|
| contact affiliation | Beijing Normal University |
| contact email | chensr@bnu.edu.cn |
| lab head | |
| Suren Chen | |
| contact affiliation | Beijing Normal University |
| contact email | chensr@bnu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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