PXD042113

PXD042113 is an original dataset announced via ProteomeXchange.

Title	Proteome-wide adaptation of Lactococcus cremoris under temperature changes or translation inhibition
Description	Growth conditions influence growth rate and the corresponding global proteome composition. It is commonly observed that a higher ribosomal content due to growth rate optimization may impact the level of metabolic proteins. In the case of Lactococcus cremoris, acidification and flavor formation are important traits of their use in cheesemaking. This study correlates the expression level of metabolic (e.g., flavor-relevant) enzymes in relation to the level of ribosomes during growth in defined medium or milk.
HostingRepository	PRIDE
AnnounceDate	2025-03-17
AnnouncementXML	Submission_2025-03-17_07:18:07.271.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sjef Boeren
SpeciesList	scientific name: Lactococcus lactis subsp. cremoris MG1363; NCBI TaxID: 416870;
ModificationList	S-carboxamidoethyl-L-cysteine; acetylated residue; monohydroxylated residue; deamidated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-10 04:29:54	ID requested
1	2025-02-17 06:25:01	announced
⏵ 2	2025-03-17 07:18:08	announced	2025-03-17: Updated project metadata.

10.1128/mbio.02990-24;

van Olst B, Boeren S, Vervoort J, Kleerebezem M, elicits immediate initiation of proteome-wide adaptation, coinciding with growth acceleration and pyruvate dissipation switching. mBio, 16(3):e0299024(2025) [pubmed]

submitter keyword: temperature, proteome allocation, Lactococcus cremoris,Protein coexpression, translation inhibitor

Sjef Boeren
contact affiliation	Wageningen University
contact email	sjef.boeren@wur.nl
lab head
Sjef Boeren
contact affiliation	Biochemistry
contact email	sjef.boeren@wur.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD042113

PRIDE project URI

• PRIDE
  1. PXD042113
     1. Label: PRIDE project
     2. Name: Proteome-wide adaptation of Lactococcus cremoris under temperature changes or translation inhibition