PXD042106
PXD042106 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Plasma proteomics-based biomarkers for predicting response to mesenchymal stem cell therapy in severe COVID-19 |
| Description | In March 2020, we performed a multicenter, randomized, double-blind phase II study of mesenchymal stem cells (MSCs) therapy in patients with severe COVID-19 (ClinicalTrials.gov: NCT04288102). Findings showed that MSC was a potentially effective therapeutic approach for patients with severe COVID-19, but not all patients responded well. To further understand the proteomic biomarkers of response to MSC therapy in patients with severe COVID-19, we characterize the proteomic profile of 58 patient pre-MSC treatment plasma samples (35 responders versus 23 non-responders) by using proteomics assays. The project aims to identify potential biomarkers for predicting response to MSC therapy by pre-MSC treatment plasma proteomic profile in severe COVID-19. |
| HostingRepository | iProX |
| AnnounceDate | 2023-05-10 |
| AnnouncementXML | Submission_2024-02-22_18:20:59.213.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tiantian Li |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-05-09 21:05:21 | ID requested | |
| ⏵ 1 | 2024-02-22 18:21:00 | announced |
Publication List
| Li TT, Yao WQ, Dong HB, Wang ZR, Zhang ZY, Yuan MQ, Shi L, Wang FS, Plasma proteomics-based biomarkers for predicting response to mesenchymal stem cell therapy in severe COVID-19. Stem Cell Res Ther, 14(1):350(2023) [pubmed] |
Keyword List
| submitter keyword: COVID-19, Mesenchymal stem cells, Proteomics |
Contact List
| Fusheng Wang | |
|---|---|
| contact affiliation | Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, No.100 Western 4th Ring Road, Beijing 100039, China. |
| contact email | fswang302@163.com |
| lab head | |
| Tiantian Li | |
| contact affiliation | Fifth Medical Center of Chinese PLA General Hospital |
| contact email | litiantian@bjmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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