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PXD042075

PXD042075 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCardiac Myofibrillogenesis is Spatiotemporally Modulated by the Molecular Chaperone UNC45B
DescriptionSarcomeres are fundamental to cardiac muscle contraction. Their impairment can elicit cardiomyopathies, leading causes of death worldwide. However, the molecular mechanism underlying sarcomere assembly remains obscure. We used human embryonic stem cell (hESC)-derived cardiomyocytes (CMs) to reveal step-wise spatiotemporal regulation of core cardiac myofibrillogenesis-associated proteins.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_09:10:32.170.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSu-Yi Tsai
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-08 21:30:32ID requested
12023-10-24 12:41:35announced
22023-11-14 09:10:33announced2023-11-14: Updated project metadata.
Publication List
Lu SH, Wu YH, Su LY, Hsu ZT, Weng TH, Wang HY, Yu C, Hsu PW, Tsai SY, Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B. Stem Cell Reports, 18(7):1405-1420(2023) [pubmed]
Keyword List
submitter keyword: Homo sapiens
Contact List
Su-Yi Tsai
contact affiliationDepartment of Life Science, National Taiwan University, Taiwan
contact emailsuyitsai@ntu.edu.tw
lab head
Su-Yi Tsai
contact affiliationNational Taiwan University
contact emailsherrywu345@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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