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PXD042045

PXD042045 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe assessment of hiPSC-derived Neural Stem Cells after a repeated-dose bisphenol A exposure
DescriptionThe present study evaluated the effects of a repeated-dose exposure of environmentally relevant BPA concentrations during the in vitro 3D neural induction of human induced pluripotent stem cells (hiPSCs), emulating a chronic exposure scenario. Quantitative proteomics at D21 revealed several differentially abundant proteins across all BPA-treated groups with important functions in NSC proliferation and maintenance.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:02:43.235.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBachuki Shashikadze
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-05-07 05:27:45ID requested
12023-09-06 10:33:49announced
22023-11-14 09:05:10announced2023-11-14: Updated project metadata.
32024-10-22 06:02:44announced2024-10-22: Updated project metadata.
Publication List
Hor, á, nszky A, Shashikadze B, Elkhateib R, Lombardo SD, Lamberto F, Zana M, Menche J, Fr, ö, hlich T, Dinny, é, s A, Proteomics and disease network associations evaluation of environmentally relevant Bisphenol A concentrations in a human 3D neural stem cell model. Front Cell Dev Biol, 11():1236243(2023) [pubmed]
10.3389/fcell.2023.1236243;
Keyword List
submitter keyword: Bisphenol A, neural stem cells, DoHAD, new approach methodology, human-induced pluripotent stem cells
Contact List
Thomas Fröhlich
contact affiliationLaboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany
contact emailfrohlich@genzentrum.lmu.de
lab head
Bachuki Shashikadze
contact affiliationLaboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany
contact emailshashikadze@genzentrum.lmu.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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