PXD041964
PXD041964 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Caspase-2 is a condensate-mediated deubiquitinase in protein quality control |
Description | When cells encounter proteome stresses, caspase-2 accumulates in a ubiquitin-rich condensate, which functions as a deubiquitinase to cleave the overloaded ubiquitinated proteins. |
HostingRepository | iProX |
AnnounceDate | 2023-09-06 |
AnnouncementXML | Submission_2025-06-13_00:20:50.706.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yingwei Ge |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF; 4800 Plus MALDI TOF/TOF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-05-03 20:55:28 | ID requested | |
1 | 2024-07-18 20:20:27 | announced | |
⏵ 2 | 2025-06-13 00:20:51 | announced | 2025-06-13: Add Publication. |
Publication List
Ge Y, Zhou L, Fu Y, He L, Chen Y, Li D, Xie Y, Yang J, Wu H, Dai H, Peng Z, Zhang Y, Yi S, Wu B, Zhang X, Zhang Y, Ying W, Cui CP, Liu CH, Zhang L, Caspase-2 is a condensate-mediated deubiquitinase in protein quality control. Nat Cell Biol, 26(11):1943-1957(2024) [pubmed] |
Keyword List
submitter keyword: caspase-2, protein quality control, deubiquitinase |
Contact List
Lingqiang Zhang | |
---|---|
contact affiliation | State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics; Beijing, 100850, China. |
contact email | zhanglq@nic.bmi.ac.cn |
lab head | |
Yingwei Ge | |
contact affiliation | State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center of Protein Sciences (Beijing), Beijing Institute of Lifeomics; Beijing, 100850, China. |
contact email | taciturnity@vip.qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |